We performed random effects meta-analyses on the change in estimated glomerular filtration rate (eGFR), serum creatinine, serum cystatin C and albumin:creatinine ratio after RDN. Studies published between January 2009 and May 2016, irrespective of study design, device used or indication for treatment were included. Our objective was to determine the change in renal function after RDN by performing a systematic review on hypertensive patients treated with RDN.Ī systematic search was performed in the Embase and MEDLINE databases to identify studies reporting on the effects of catheter-based RDN on renal outcome. The invasive nature of RDN and the use of contrast agents raise concerns about potential consequent kidney damage. Catheter-based renal denervation (RDN) is a possible treatment to lower blood pressure.
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